Association between mental illness, obesity and metabolic syndrome.effect of the treatment with psychotropic drugs

Authors

  • Silvia Wikinski Médica psiquiatra (UBA) Profesora Adjunta de Farmacología, 1era. Cátedra de Farmacología, Facultad de Medicina (UBA) Investigadora Principal del CONICET. Instituto de Farmacología, Facultad de Medicina (UBA)

Keywords:

Metabolic comorbidity in Psychiatry, Adipokines, Weight gain, Antidepressants, Antipsychotics, Mood stabilizers

Abstract

Persons with mental disorders present higher morbimortality than that observed in general population. Among the factors contributing with this situation we can mention an increase in the incidence of obesity and metabolic syndrome, with their burden of cardiovascular and cancer risks. This review summarizes the evidence about the comorbid presence of schizophrenia, unipolar depression and bipolar disorder on one side and metabolic syndrome or obesity on the other. We also review the different causes of such comorbidity, in particular the adverse effects of psychotropic drugs, diverse biological factors predisposing to the increase in body weight and the measures that can be taken in order to attenuate or prevent metabolic disease in persons affected by mental illness.

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Published

2023-04-30

How to Cite

Wikinski, S. (2023). Association between mental illness, obesity and metabolic syndrome.effect of the treatment with psychotropic drugs. Vertex Revista Argentina De Psiquiatría, 29(138, mar.-abr.), 120–127. Retrieved from https://revistavertex.com.ar/ojs/index.php/vertex/article/view/374

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