Toxic epidermal necrolysis: idiosyncratic reaction to drugs

Authors

  • Julio César Rotondaro Servicio de clínica médica, Instituto de investigaciones médicas Alfredo Lanari
  • Aaron Cristian Kim Servicio de clínica médica, Instituto de investigaciones médicas Alfredo Lanari
  • Paula Monti Servicio de clínica médica, Instituto de investigaciones médicas Alfredo Lanari
  • Mónica Pazos Servicio de dermatología, Instituto de investigaciones médicas Alfredo Lanari
  • Carla Gazzi Servicio de patología, Instituto de investigaciones médicas Alfredo Lanari
  • Rodolfo López Unidad de Cuidados Intensivos, Instituto de investigaciones médicas Alfredo Lanari
  • Fernando Riccioppo Servicio de salud mental, Instituto de investigaciones médicas Alfredo Lanari
  • Daniel Fadel Servicio de salud mental, Instituto de investigaciones médicas Alfredo Lanari

DOI:

https://doi.org/10.53680/vertex.v32i152.42

Keywords:

Anticonvulsants, Divalproate sodium, Hypersensitivity, Lamotrigine, Necrolysis toxic epidermal, Steven Johnson syndrome

Abstract

Toxic epidermal necrolysis (NET) and Steven Johnson syndrome (SJS) are infrequent mucocutaneous hypersensitivity reactions with systemic involvement. They are predominantly caused by drugs. We report the case of a patient over 60 years of age who presented with extensive mucocutaneous and ophthalmic injury with hemodynamic failure, associated with the rapid onset of lamotrigine in a short period of time. Although the incidence is low, the mortality rate is high. It requires early suspicious and diagnosis in addition to an interdisciplinary therapeutic approach.

Downloads

Download data is not yet available.

Downloads

Published

2021-07-02

How to Cite

Rotondaro, . J. C., Kim, A. C., Monti, P., Pazos, M., Gazzi, C., López, R., Riccioppo, F., & Fadel, D. (2021). Toxic epidermal necrolysis: idiosyncratic reaction to drugs. Vertex Revista Argentina De Psiquiatría, 32(152, abr.-jun.), 20–23. https://doi.org/10.53680/vertex.v32i152.42

Issue

Vol. 32 No. 152, abr.-jun. (2021)

Section

Artículos