Sleep Disorders and depression in Parkinson’s Disease

Abstract

Objectives: Sleep disorders are common in Parkinson’s disease (PD). To diagnose sleep disturbances analyzing the sleep macrostructure and other variables in PD. Method: The cross-sectional, retrospective study in PD patients. Sociodemographic, clinical/pharmacological variables, Epworth sleepiness scale (ESS), Beck depression index (BDI) and polysomnography of patients with Parkinson’s disease. Frequency, mean, standard deviation analysis were obtained. The variables were compared using t test student, univariate ANOVA and chi-square. A p<0.05 was considered significant. SPSS (Chicago SPSS Inc .) 18 was used. The n were 44 patients, 33 men, mean age 71 (range 52-90), ESS 7.7±6 (normal), BDI 13±8 points (pathological). Conclusions: At older age, the time awake after sleep began (p=0.03) was greater and lower sleep efficiency (p=0.02).The average percentage of stage of N3 sleep was 37.2% in women vs 24.7% in men (p=0.02). Hypopnea apnea index was pathological grade at 79.5% (n=35).We diagnose apnea hypopnea syndrome in the majority, insomnia and REM parasomnias. The increase in the percentage of stage N3 was rarely reported in the literature. At older age were more changes in the macroestructure and more sleep disturbances